Holy Grail of Biology? Scientists Find How To Stop Aging of Human Cells

The study is published in the journal Aging and describes how delivering hydrogen sulfide directly to mitochondria can allow old cells to regain the dividing abilities of younger cells.

A group of scientists has found a way to reverse cell aging by supplying hydrogen sulfide in small doses.

The experts used a modern technology known as “molecular zip code” that allows the necessary molecule to be sent directly into the mitochondria, structures that produce energy in the cells.

The results of the study were published in an article by The Conversation.

The acid, also known as hydrogen sulfide, is a toxic compound in large quantities.

However, the team released it in small amounts to treat aged cells.

This distribution of sulfur increased the levels of the so-called gene splicing factors.

The purpose was to eliminate the damaged cells and not prolong their life.

According to the authors, damaged cells not only fail to function properly but also put at risk the functioning of those around them.

“We still don’t fully comprehend why cells become senescent as we age, but harm to DNA, exposure to inflammation and injury to the protecting molecules at the end of the chromosomes – the telomeres – have all been inferred,” the authors wrote in an article published by The Conversation.

“More recently, people have proposed that one driver of senescence may be a loss of our ability to turn genes on and off at the right time and in the right place,” explained reseaarchers.

The modern approach associates the accumulation of senescent cells in tissues and organs with much of the common chronic diseases that humans suffer from, such as cancer, diabetes, and dementia, the article explains.
Controlling it is a challenge for the scientific world since it means being able to activate and deactivate genes at the right time and in the right place by means of regulators.

“We are hopeful that in using molecular tools such as this, we will be able to eventually remove senescent cells in living people, which may allow us to target multiple age-related diseases at once. This is some way in the future yet, but it’s an exciting start,” the researchers concluded.

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