An image of the most complex synthetic microparticle in the world, made from curved gold-cysteine nanosheets. Image Credit: Wenfeng Jiang, Kotov Lab, University of Michigan.

This is the Most Complex Synthetic Microparticle in the World And it Outdoes Nature

It's so complex that it is found to even outdo nature's intricacy.

Synthetic microparticles, more complex than some of the most complex found in nature, have been produced by an international team led by scientists from the University of Michigan. They also investigated how that complexity arises and devised a way to measure it, something never achieved until now.

The findings, published in Science, pave the way for more stable mixtures of fluids and particles, such as paints, and new ways of twisting light, a prerequisite for holographic projectors. The particles are made up of twisted spikes arranged into a ball a few microns, or millionths of a meter in diameter.

Mother nature turns out to be a very talented creator when it comes to the complexity of the nano- and microscales, with pointed structures such as plant pollen, immune cells, and some viruses being perfect examples of that.

Among the most complex natural particles on the scale of the new synthetic particles are pointy coccolithophores. A few microns in diameter, this type of algae is known to build intricate limestone shells around it. To better understand the rules that govern how particles like these grow, scientists and engineers try to reproduce them in the laboratory.

But until now, there was no formal way to measure the complexity of the results.

“Numbers rule the world, and being able to rigorously describe spiky shapes and put a number on complexity enables us to use new tools like artificial intelligence and machine learning in designing nanoparticles,” revealed Nicholas Kotov, the Joseph B. and Florence V. Cejka Professor of Engineering at U-M, who led the study.

The group of researchers made use of the new framework to describe how their particles could become even more complex than coccolithophores. André Farias de Moura, professor of chemistry at the Federal University was in charge of studying the quantum properties of the particles, as well as the forces acting on the nanoscale of its building blocks.

The researchers introduced chirality by coating nanoscale hold sulfide sheets. They were able to create the building blocks of the particles using an amino acid called cysteine.

Cysteine comes in two mirror-image forms, one driving the gold sheets to stack with a clockwise twist, and the other tending toward a counterclockwise twist. In the case of the most complex particle, a spiky ball with twisted spines, each gold sheet was coated with the same form of cysteine, explains

The team of scientists also monitored other interactions. By using flat nanoparticles, they created spikes that were flat instead of round. Scientists also made use of electrically charged molecules to ensure that the nanoscale components turned into larger particles, larger than a few hundred nanometers in diameter, due to repulsion.

“These laws often conflict with each other, and the complexity emerges because these communities of nanoparticles have to satisfy all of them,” revealed Nicholas Kotov, professor of materials science and engineering and macromolecular science and engineering.

Scientists shave created the most complex synthetic microparticle, a synthetic that outdoes nature’s most complex examples.

Written by Curiosmos

Created with love for the passionately Curious. was created with two words in mind: Curious and Cosmos. See what we did there? Curious: /ˈkjʊərɪəs/ eager to know or learn something. Something strange; unusual. Cosmos /ˈkɒzmɒs/ the universe seen as a well-ordered whole. A system of thought. You could say that Curiosmos is the Cosmos for the curious reader.

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